Evolence®

The collagen-based filler Evolence®, used to correct moderate to more pronounced wrinkles, was discontinued in 2009 by its distributor, Johnson & Johnson. Hyaluronic-based fillers Juvederm®, Perlane®, Restylane® , and Radiesse® provide the same immediate benefit of softening facial lines and creases and adding increased volume to flat or recessed areas. Radiesse® and Sculptra® Aesthetic have the added benefit of increasing collagen production.